Successful extirpation of a perforated esophagus after chemo radiotherapy in infiltrative ulcerative squamous cell carcinoma

Esophageal cancer is one of the most aggressive malignant neoplasms gastrointestinal tract, occupying eighth place in structure morbidity worldwide. Despite comprehensive approaches to treatment, mortality continues grow both gender groups, which moves this pathology sixth position from tumors. A lot patients undergo radiation therapy preoperative period or an independent version due peculiarities localization tumor spread process. One serious complications disease on background ongoing conservative perforation esophagus, which, according literature, can develop 5.6 33 % cases, and risk factors for development complication are infiltrative-u lcerative form cancer, stage T3–4 presence esophageal stenosis, as well use chemotherapy drugs such fluorouracil cisplatin. The article describes a clinical case patient with squamous cell carcinoma esophagus chemoradiotherapy. total focal dose (TFD) at time was 24 Gy. As result additional examination, revealed developed interdisciplinary council decided immediate surgical intervention, during extirpation gastro- esophagostomy performed. discharged 15th day satisfactory condition recommendation conduct IHC study PD-L1 expression determine further management tactics. This demonstrates role infiltrative- ulcerative growth, disease, treatment perforation; important task prehospital selection thorough examination specialized oncological centers exclude possible process above treatment.